Outbreak Sim Games
Discover 456 outbreak sim-tagged games on Steam. Find the best games with this tag.
Discover 456 outbreak sim-tagged games on Steam. Find the best games with this tag.
Explore 456 games tagged with outbreak sim

Plague Inc: Evolved is a unique mix of high strategy and terrifyingly realistic simulation. Your pathogen has just infected 'Patient Zero' - now you must bring about the end of human history by evolving a deadly, global Plague whilst adapting against everything humanity can do to defend itself.

Choose any real region from the world. Choose your base of operations, then rebuild and readapt the buildings around you to create a self-sustaining settlement. Take charge of a group of survivors from your city. And when the night falls - Defend the zone from the infected!

WARNING. Stay inside. Lock your doors. Close the blinds. Only let humans in. Eliminate all Visitors. An anxiety horror about paranoia in the End of Times.

Manage the night shift of an ER during the apocalypse, solo or with friends online: Diagnose patients. Design and grow your hospital, and defend against the undead while treating the living. If you're a creator, connect the game to Twitch and make the audience your patients for even more fun!

No More Room in Hell 2 is an intense 8 player zombie shooter. Overcome the endless undead. Avoid infection. Survive hell together.

The post-apocalyptic dark comedy is back - remastered and even more radioactive than before! Scavenge supplies, rescue your family, and stay alive in your fallout shelter. Make difficult decisions, hunt mutant roaches... and maybe survive. Or not.

Can you rebuild civilisation after a zombie apocalypse? From the creator of Plague Inc. comes a unique blend of strategic simulation, survival city builder and ‘mini 4X’. Build settlements, harvest resources and shape society as you lead Humanity out of the darkness.

Survive the Zombies War in this RPG game of Apocalypse and Survival

A strategy game with a new kind of enemy, Calyx puts you in charge of a space mining outpost, locked in battle against powerful plant-aliens. Build your base, gather resources, assemble your forces, and take on the Calyx. With only an out-of-date AI for company, can you survive?

60 Parsecs! is an Atomic Space Age adventure of scavenge and survival. Keep your crew alive and ready for action. Make difficult choices, face soup shortages and other horrors of outer space. And maybe reach your destination. Or not.

Rebuild a ruined city in this post-apocalyptic mix of strategy and simulation. Manage survivors, scavenge for food and supplies, deal with rival gangs, illness, interpersonal strife and zombie attacks.

Bio Inc.: Redemption is a realistic simulation and strategy game in which you make life or death decisions. Create a deadly illness to infect and torment your victim or play as the head of a medical team and hopefully find a cure to save your human patient. Will you be the plague or preserve humanity?

Kill everyone in the world with a guillotine… on a cursed Win98 desktop.

This is an open-world zombie survival game set in a quarantined city. You play as a student left behind due to missing the evacuation convoy. Together with classmates and other survivors, you must defend the school, survive, and await rescue.

60 Seconds! is a dark comedy atomic adventure of scavenge and survival. Collect supplies and rescue your family before the nuke hits. Stay alive in your fallout shelter. Make difficult decisions, ration food and hunt mutant cockroaches. And maybe survive. Or not.

A campy, crazy pixelart zombie apocalypse arcade sim where you're the bad guy. Drop your virus and spread it across the globe while you unlock a whole horde of bizarre undead to do your bidding.

Explore infinite possibilities with INFINITE LIVES - where superhumans and subhumans fight for control of the ultimate shared universe! Bursting into the 3rd dimension brings new powers with unprecedented freedom, in a vicious cycle that never ends...

Take on the role of a Dark Elder God and lead your agents to bring about an apocalypse in a fantasy world. Work in the shadows, avoiding the heroes who will try to stop you, as you bring about plague and famine, ice age and volcanic destruction, madness and never ending night.

Be the Zombie. Kick A** and Take Brains.

Build, manage and optimise intergalactic hospitals! Recruit staff to satisfy the whims of various alien species, and cure their bizarre illnesses - for money! Save the (literal) Galaxy in story mode, or head into sandbox to design the hospital of your dreams.